Internal tandem duplication in Fms-like tyrosine kinase 3 (FLT3-ITD) is the most frequent mutation observed in acute myeloid leukemia (AML) and correlates with poor prognosis.FLT3 tyrosine kinase inhibitors are promising for targeted therapy.Here, we investigated mechanisms dampening the response to the FLT3 inhibitor quizartinib, which is specific
This study explores public discourse surrounding the January 2025 California wildfires by analyzing high-engagement YouTube comments.Leveraging sentiment analysis, misinformation detection, and topic modeling, this research identifies dominant emotional tones, thematic patterns, and the prevalence of Timotion cable misinformation in discussions.The
Integrated fiber-wireless (FiWi) should be regarded Baja Hoodies as a promising access network architecture in future 5G networks, and beyond; this due to its seamless combination of flexibility, ubiquity, mobility of the wireless mesh network (WMN) frontend with a large capacity, high bandwidth, strong robustness in time, and a wavelength-division
Objective: Public health surveillance is an important aspect of outbreak early warning based on prediction models.The present study compares a hybrid model based on discrete wavelet transform (DWT) and ARIMA (Autoregressive Integrated Moving Average) for predicting incidence cases due to COVID-19.Methods: In the current cross-sectional stuady based
Typhoid fever is an infectious disease that affects humanity worldwide; it is particularly dangerous in areas with communities of a lower socio-economic status, where many individuals are exposed to a dirty environment and unclean food.A mathematical model is formulated to analyze the impact of control measures such as vaccination of susceptible hu